sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dzz | ADP | Plasmid partitioning protein ParF |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 1.000 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.638 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.483 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.469 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.466 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.466 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.465 | |
| 5ftc | ADP | TPR domain protein | / | 0.465 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.464 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.459 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.457 | |
| 3ieu | GDP | GTPase Era | / | 0.457 | |
| 4ohv | ANP | Protein clpf-1 | / | 0.457 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.455 | |
| 4qbg | AP5 | Adenylate kinase | / | 0.452 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.451 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.451 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4oi2 | ADP | Protein clpf-1 | / | 0.447 | |
| 2qaj | AP5 | Adenylate kinase | / | 0.445 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1w5t | ADP | ORC1-type DNA replication protein 2 | / | 0.442 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 5aga | ANP | DNA polymerase theta | / | 0.442 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.441 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.440 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.440 |