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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4dk70KSOxysterols receptor LXR-beta

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4dk70KSOxysterols receptor LXR-beta/1.000
1pqc444Oxysterols receptor LXR-beta/0.604
1pq944BOxysterols receptor LXR-beta/0.529
1p8dCO1Oxysterols receptor LXR-beta/0.527
2aclL05Oxysterols receptor LXR-alpha/0.523
1upw444Oxysterols receptor LXR-beta/0.508
1pq6965Oxysterols receptor LXR-beta/0.503
5irnADPNucleotide binding oligomerization domain containing 2/0.485
3ipq965Oxysterols receptor LXR-alpha/0.478
2getCOKPantothenate kinase2.7.1.330.456
1hb1OCVIsopenicillin N synthase1.21.3.10.450
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3w0hW12Vitamin D3 receptor/0.444
1dghNDPCatalase1.11.1.60.441
3wleNAD(R)-specific carbonyl reductase/0.441
4kbyC2EStimulator of interferon genes protein/0.441