sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 1.000 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.642 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.525 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.512 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.496 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.472 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.466 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.462 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.460 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.452 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.451 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.447 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.441 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.440 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.440 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.440 |