sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b1f | KRH | Glutamate racemase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4b1f | KRH | Glutamate racemase | / | 1.000 | |
| 2jfz | 003 | Glutamate racemase | / | 0.581 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.493 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.482 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.473 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.465 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.458 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.457 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.451 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.450 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.450 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.450 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.447 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.446 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 4o7u | THF | Thymidylate synthase | / | 0.446 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.446 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.444 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.444 | |
| 3lu8 | IQX | Serum albumin | / | 0.444 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.444 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.442 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.440 |