scPDB - Distribution of Binding site Similarity values of 4an9 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
4an3	5Y0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.611
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.605
4anb	YQY	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.605
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.587
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.574
3pp1	IZG	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.573
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.553
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.547
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.547
3vvh	4BM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.546
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.546
2p55	MRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.545
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.545
3dy7	1CX	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.540
3dv3	MEK	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.535
4l2i	FAD	Electron transfer flavoprotein alpha/beta-subunit	/	0.467
3hv5	R24	Mitogen-activated protein kinase 14	/	0.464
4f9m	FCM	Peroxisome proliferator-activated receptor gamma	/	0.457
4hee	14R	Peroxisome proliferator-activated receptor gamma	/	0.457
3vnt	0JA	Vascular endothelial growth factor receptor 2	2.7.10.1	0.445
2ycq	UPX	Serine/threonine-protein kinase Chk2	2.7.11.1	0.443
3p6n	DSO	Camphor 5-monooxygenase	1.14.15.1	0.442
1iep	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.441
3q8x	UD1	Toxin zeta	/	0.440
4fc0	0T2	Serine/threonine-protein kinase B-raf	2.7.11.1	0.440
4mcv	29K	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.440