scPDB - Distribution of Binding site Similarity values of 4an2 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
4anb	YQY	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.587
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.562
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.559
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.558
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.555
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.547
4an3	5Y0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.544
3dv3	MEK	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.540
3pp1	IZG	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.530
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.511
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.508
2p55	MRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.503
3dy7	1CX	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.499
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.499
3sls	77D	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.496
3vvh	4BM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.477
3ol5	SAW	Camphor 5-monooxygenase	1.14.15.1	0.468
2f4b	EHA	Peroxisome proliferator-activated receptor gamma	/	0.463
1zgy	BRL	Peroxisome proliferator-activated receptor gamma	/	0.462
1k6c	MK1	Gag-Pol polyprotein	3.4.23.16	0.461
3v9y	24L	Peroxisome proliferator-activated receptor gamma	/	0.459
2ev9	NAP	Shikimate dehydrogenase (NADP(+))	/	0.457
4jvf	17X	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.457
3p6n	DSO	Camphor 5-monooxygenase	1.14.15.1	0.456
3wmx	NAD	NAD dependent epimerase/dehydratase	/	0.453
1i7i	AZ2	Peroxisome proliferator-activated receptor gamma	/	0.451
4f9m	FCM	Peroxisome proliferator-activated receptor gamma	/	0.450
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.448
1rf9	DBR	Camphor 5-monooxygenase	1.14.15.1	0.448
1k6p	XN3	Gag-Pol polyprotein	3.4.23.16	0.447
3p6m	DSO	Camphor 5-monooxygenase	1.14.15.1	0.447
3sz0	FAD	Sulfide-quinone reductase	/	0.447
4q73	FAD	Bifunctional protein PutA	/	0.447
3zk5	Z18	Cytochrome P450 monooxygenase PikC	/	0.446
3kpk	FAD	Sulfide-quinone reductase	/	0.445
5hws	NAP	2-dehydropantoate 2-reductase	/	0.445
3t14	FAD	Sulfide-quinone reductase	/	0.444
3t2y	FAD	Sulfide-quinone reductase	/	0.444
2gmh	FAD	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	1.5.5.1	0.443
2jd1	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	/	0.443
1re9	DSO	Camphor 5-monooxygenase	1.14.15.1	0.442
3p6o	ETG	Camphor 5-monooxygenase	1.14.15.1	0.442
4q71	FAD	Bifunctional protein PutA	/	0.442
4ez8	DHF	Thymidylate synthase	2.1.1.45	0.441