scPDB - Distribution of Binding site Similarity values of 4a16 entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4a16	H34	Acetylcholinesterase	3.1.1.7

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4a16	H34	Acetylcholinesterase	3.1.1.7	1.000
2xui	TZ5	Acetylcholinesterase	3.1.1.7	0.499
1ut6	A8N	Acetylcholinesterase	3.1.1.7	0.496
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.476
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.474
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.472
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.471
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.469
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.468
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.467
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.465
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.465
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.464
4ara	C56	Acetylcholinesterase	3.1.1.7	0.462
4arb	C57	Acetylcholinesterase	3.1.1.7	0.457
2xuk	TZ5	Acetylcholinesterase	3.1.1.7	0.456
2ha6	SCK	Acetylcholinesterase	3.1.1.7	0.452
2cmf	F11	Acetylcholinesterase	3.1.1.7	0.451
1eve	E20	Acetylcholinesterase	3.1.1.7	0.450
1w4l	GL8	Acetylcholinesterase	3.1.1.7	0.446
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.443