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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3zuyTCHTransporter

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3zuyTCHTransporter/1.000
3zuxTCHTransporter/0.688
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.476
3a1nNADNDP-sugar epimerase/0.466
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.465
4r21STRCytochrome P450 family 17 polypeptide 2/0.448
1jipKTN6-deoxyerythronolide B hydroxylase/0.447
2znnS44Peroxisome proliferator-activated receptor alpha/0.442
4ryvZEAProtein LlR18A/0.440