scPDB - Distribution of Binding site Similarity values of 3wsw entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3wsw	NAD	L-lactate dehydrogenase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3wsw	NAD	L-lactate dehydrogenase	/	1.000
2a92	NAI	L-lactate dehydrogenase	/	0.523
2aa3	AP0	L-lactate dehydrogenase	/	0.496
2x0i	NAI	Malate dehydrogenase	/	0.487
4l4s	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.464
1ez4	NAD	L-lactate dehydrogenase	1.1.1.27	0.463
1mp0	NAD	Alcohol dehydrogenase class-3	1.1.1.1	0.462
4gl4	NAI	Alcohol dehydrogenase class-3	/	0.462
1t2c	NAI	L-lactate dehydrogenase	1.1.1.27	0.461
4rls	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.451
3gvh	NAD	Malate dehydrogenase	/	0.444
3h3f	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.440