Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vrzVRZTyrosine-protein kinase HCK2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vrzVRZTyrosine-protein kinase HCK2.7.10.21.000
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.618
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.607
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.581
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.570
3vs1VSATyrosine-protein kinase HCK2.7.10.20.555
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.551
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.538
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.537
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.537
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.536
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.531
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.530
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.522
3vs3VSETyrosine-protein kinase HCK2.7.10.20.516
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
3vryB43Tyrosine-protein kinase HCK2.7.10.20.490
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.486
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.479
2c6eHPMAurora kinase A2.7.11.10.479
4i22IREEpidermal growth factor receptor2.7.10.10.476
3w2sW2REpidermal growth factor receptor2.7.10.10.473
4nka2K7Fibroblast growth factor receptor 1/0.472
3w33W19Epidermal growth factor receptor2.7.10.10.467
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.466
3poz03PEpidermal growth factor receptor2.7.10.10.462
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.460
3w2rW2REpidermal growth factor receptor2.7.10.10.459
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.458
4id71G0Activated CDC42 kinase 1/0.455
3w18N13Aurora kinase A2.7.11.10.451
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1xkkFMMEpidermal growth factor receptor2.7.10.10.448
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.448
2hk51BMTyrosine-protein kinase HCK2.7.10.20.441