scPDB - Distribution of Binding site Similarity values of 3v04 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.658
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.650
3dy7	1CX	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.647
2p55	MRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.645
3pp1	IZG	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.644
4an3	5Y0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.606
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.595
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.590
4anb	YQY	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.580
3vvh	4BM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.578
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.564
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.563
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.551
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.535
3dv3	MEK	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.529
3amb	VX6	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.485
4fsr	HKC	Serine/threonine-protein kinase Chk1	2.7.11.1	0.473
4fti	H7K	Serine/threonine-protein kinase Chk1	2.7.11.1	0.463
4l2i	FAD	Electron transfer flavoprotein alpha/beta-subunit	/	0.462
1zgy	BRL	Peroxisome proliferator-activated receptor gamma	/	0.461
3t1t	GDP	Probable gliding protein mglA	/	0.456
3lin	E13	Protease	/	0.455
4bcm	T7Z	Cyclin-dependent kinase 2	2.7.11.22	0.453
4gt3	ATP	Mitogen-activated protein kinase 1	2.7.11.24	0.453
3qa2	XNA	Ketohexokinase	/	0.452
3vnt	0JA	Vascular endothelial growth factor receptor 2	2.7.10.1	0.451
3zk5	Z18	Cytochrome P450 monooxygenase PikC	/	0.451
3ezv	EZV	Cyclin-dependent kinase 2	2.7.11.22	0.447
3zkp	ERB	Erythromycin C-12 hydroxylase	1.14.13.154	0.447
3kq7	KQ7	Mitogen-activated protein kinase 14	/	0.446
2fle	AI	Protease	/	0.445
3q92	XNB	Ketohexokinase	/	0.443
1i7i	AZ2	Peroxisome proliferator-activated receptor gamma	/	0.442
1iep	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.442
2hog	710	Serine/threonine-protein kinase Chk1	2.7.11.1	0.442
3qai	XNN	Ketohexokinase	/	0.442
4f9m	FCM	Peroxisome proliferator-activated receptor gamma	/	0.442
4yao	FMN	NADPH--cytochrome P450 reductase	/	0.442
2idw	017	Protease	/	0.440
3vjh	J35	Peroxisome proliferator-activated receptor gamma	/	0.440
5dpv	SKE	Aurora kinase A	2.7.11.1	0.440