sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tkl | GTP | Ras-related protein Rab-1A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3tkl | GTP | Ras-related protein Rab-1A | / | 1.000 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.530 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.525 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.519 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.513 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.511 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.503 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.502 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.498 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.494 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.485 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.483 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.481 | |
| 1u0h | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.480 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.480 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.479 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.478 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.474 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.473 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.472 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.472 | |
| 3lbn | GNP | GTPase HRas | / | 0.472 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.472 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.471 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.469 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.465 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.463 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.462 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.461 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.458 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.457 | |
| 4nyi | GNP | GTPase HRas | / | 0.457 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.455 | |
| 1lfd | GNP | GTPase HRas | / | 0.453 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.452 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.452 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.450 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.449 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.448 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.448 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.447 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.445 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.444 | |
| 5b2z | GNP | GTPase HRas | / | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.440 | |
| 3v4f | GNP | GTPase HRas | / | 0.440 |