sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3stv | 3HO | Methylketone synthase I |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3stv | 3HO | Methylketone synthase I | / | 1.000 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.617 | |
| 3stx | BKA | Methylketone synthase I | / | 0.594 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.551 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.479 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.458 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.443 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.440 |