Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3sbeGNPRas-related C3 botulinum toxin substrate 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3sbeGNPRas-related C3 botulinum toxin substrate 1/1.000
4mitGTPRho-related protein racC/0.617
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.568
1e96GTPRas-related C3 botulinum toxin substrate 1/0.554
4lhwGNPRas-related protein Rab-8A/0.554
5b2zGNPGTPase HRas/0.539
3i3sGNPGTPase HRas/0.536
2c5lGTPGTPase HRas/0.534
3a6pGTPGTP-binding nuclear protein Ran/0.534
3rabGNPRas-related protein Rab-3A/0.531
4ol0GTPGTP-binding nuclear protein Ran/0.530
3lbnGNPGTPase HRas/0.527
3v4fGNPGTPase HRas/0.527
1s1cGNPTransforming protein RhoA/0.523
4nyiGNPGTPase HRas/0.523
4dltGNPGTPase HRas/0.522
5dhaGNPGTP-binding nuclear protein Ran/0.522
3ddcGNPGTPase HRas/0.518
4k81GTPGTPase HRas/0.518
3kkoGNPRas-related protein M-Ras/0.517
1xtsGTPGTP-binding protein Rheb/0.514
3kz1GSPTransforming protein RhoA/0.513
3oivGNPGTPase HRas/0.513
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.511
1kmqGNPTransforming protein RhoA/0.510
3bbpGTPRas-related protein Rab-6A/0.509
2rgcGNPGTPase HRas/0.506
2rgbGNPGTPase HRas/0.504
3eg5GNPCell division control protein 42 homolog/0.504
3oiuGNPGTPase HRas/0.504
4cymGCPRas-related protein Rab-32/0.503
2gilGTPRas-related protein Rab-6A/0.502
4js0GNPCell division control protein 42 homolog/0.502
1yzqGNPRas-related protein Rab-6A/0.501
3pitGNPRas-related protein M-Ras/0.499
3wyfGTPGTP-binding nuclear protein/0.499
4g0nGNPGTPase HRas/0.499
3a58GNPGTP-binding protein RHO1/0.498
3w3zGTPGTP-binding nuclear protein Ran/0.498
2zetGTPRas-related protein Rab-27B/0.497
3ea5GDPGTP-binding nuclear protein Ran/0.495
5jljGNPGTP-binding nuclear protein Ran/0.495
1zd9GDPADP-ribosylation factor-like protein 8A/0.493
3rs7GNPGTPase HRas/0.492
1cxzGSPTransforming protein RhoA/0.491
3lbhGNPGTPase HRas/0.491
1zc4GNPRas-related protein Ral-A/0.490
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.489
3tnfGNPRas-related protein Rab-8A/0.488
1zc3GNPRas-related protein Ral-A/0.487
4dlwGNPGTPase HRas/0.487
3rs0GNPGTPase HRas/0.486
1zbdGTPRas-related protein Rab-3A/0.485
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.485
3lawGNPRas-related protein Rab-7a/0.485
4gzmGSPRas-related C3 botulinum toxin substrate 1/0.485
3x1zGNPRas-related protein Rap-1b/0.484
3k8yGNPGTPase HRas/0.482
4xoiGTPTransforming protein RhoA/0.481
2gcpGSPRho-related GTP-binding protein RhoC/0.480
3nbzGTPGTP-binding nuclear protein Ran/0.480
3rs5GNPGTPase HRas/0.480
4hdoGNPRas-related protein Rap-1b/0.480
1yhnGTPRas-related protein Rab-7a/0.479
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.479
3oesGNPGTPase RhebL1/0.479
1xtrGNPGTP-binding protein Rheb/0.478
4o25GTPGTP-binding protein Rheb/0.478
5hpyGDPTransforming protein RhoA/0.478
3e5hGNPRas-related protein Rab-28/0.477
1vg8GNPRas-related protein Rab-7a/0.476
4rkfGNPRas-related protein Rab-3/0.475
2rgeGNPGTPase HRas/0.474
4nyjGNPGTPase HRas/0.474
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.473
4gzlGNPRas-related C3 botulinum toxin substrate 1/0.473
4qxaGTPRas-related protein Rab-9A/0.473
5difGNPGTP-binding nuclear protein Ran/0.473
4kvgGTPRas-related protein Rap-1A/0.472
1m7bGTPRho-related GTP-binding protein RhoE/0.471
3kucGDPRas-related protein Rap-1A/0.471
1g17GNPRas-related protein SEC4/0.470
4dsnGCPGTPase KRas/0.470
2bkuGTPGTP-binding nuclear protein Ran/0.463
2fe4GDPRas-related protein Rab-6B/0.463
4o2lGTPGTP-binding protein Rheb/0.462
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.461
1t91GTPRas-related protein Rab-7a/0.460
3lbiGNPGTPase HRas/0.460
3oiwGNPGTPase HRas/0.459
3th5GNPRas-related C3 botulinum toxin substrate 1/0.459
3tklGTPRas-related protein Rab-1A/0.459
2clsGTPRho-related GTP-binding protein Rho6/0.458
3bc1GNPRas-related protein Rab-27A/0.458
3l8yGNPGTPase HRas/0.458
1k5dGNPGTP-binding nuclear protein Ran/0.457
1a2bGSPTransforming protein RhoA/0.456
1ibrGNPGTP-binding nuclear protein Ran/0.455
1z2cGNPRho-related GTP-binding protein RhoC/0.454
1oixGDPRas-related protein Rab-11A/0.453
3rslGNPGTPase HRas/0.453
3pqbVGPPutative oxidoreductase/0.451
3rs4GNPGTPase HRas/0.451
3tsoGNPRas-related protein Rab-25/0.450
3c14GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.448
4hdqGNPRas-related protein Rap-1b/0.448
4dlvGNPGTPase HRas/0.446
1uadGNPRas-related protein Ral-A/0.443
2ffqGSPRas-related protein Rab-6B/0.443
1gwnGTPRho-related GTP-binding protein RhoE/0.441
3ix4TX1Transcriptional activator protein LasR/0.441
4uj3GNPRas-related protein Rab-11A/0.441
4o2rGDPGTP-binding protein Rheb/0.440