sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rox | TEP | NAD(P)H-hydrate epimerase | 5.1.99.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rox | TEP | NAD(P)H-hydrate epimerase | 5.1.99.6 | 1.000 | |
| 3roe | THM | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.574 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.477 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.472 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.469 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.454 | |
| 4p5f | AR6 | Inosine-uridine nucleoside N-ribohydrolase | / | 0.454 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 1n2v | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 2j5s | KTA | Alr4455 protein | / | 0.441 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.441 |