sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3r5y | F42 | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3r5y | F42 | Uncharacterized protein | / | 1.000 | |
| 5dp2 | NAP | CurF | / | 0.486 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.480 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.470 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.466 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.463 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.459 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.459 | |
| 3r5w | F42 | Deazaflavin-dependent nitroreductase | / | 0.457 | |
| 1osv | CHC | Bile acid receptor | / | 0.456 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.452 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.452 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.447 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.447 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.446 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.446 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.444 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 |