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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.60

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.601.000
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.714
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.680
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.677
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.658
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.651
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.616
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.584
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.584
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.575
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.557
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.453
3n0hTOPDihydrofolate reductase1.5.1.30.445
4iarERM5-hydroxytryptamine receptor 1B/0.443
4e0u0MVCyclic dipeptide N-prenyltransferase/0.440