Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.21.000
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.601
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.596
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.574
2p55MRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.571
3dy71CXDual specificity mitogen-activated protein kinase kinase 12.7.12.20.554
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.541
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.541
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.535
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.524
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.521
4anbYQYDual specificity mitogen-activated protein kinase kinase 12.7.12.20.520
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.515
4an2EUIDual specificity mitogen-activated protein kinase kinase 12.7.12.20.515
4lmnEUIDual specificity mitogen-activated protein kinase kinase 12.7.12.20.515
3vvh4BMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.489
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.472