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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3p8hP8HLethal(3)malignant brain tumor-like protein 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3p8hP8HLethal(3)malignant brain tumor-like protein 1/1.000
5fd8A5APutative carboxypeptidase yocD/0.465
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.464
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.464
2xuqTZ4Acetylcholinesterase3.1.1.70.451
4e2yJHZMethyltransferase/0.449
2xugTZ4Acetylcholinesterase3.1.1.70.442
2jf0HBPAcetylcholinesterase3.1.1.70.440
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.440
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.440