sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3oyz | ACO | Malate synthase | 2.3.3.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3oyz | ACO | Malate synthase | 2.3.3.9 | 1.000 | |
| 1p7t | ACO | Malate synthase G | / | 0.515 | |
| 4l9z | COA | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.515 | |
| 4l9y | 1VU | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.495 | |
| 4l80 | 1VU | Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase | 4.1.3.24 | 0.476 | |
| 2gq3 | COA | Malate synthase G | / | 0.464 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.462 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 |