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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ogqAB1Pol polyprotein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3ogqAB1Pol polyprotein/1.000
1wbk568Pol protein/0.518
1idb0DOGag-Pol polyprotein/0.512
1w5yBE6Gag-Pol polyprotein3.4.23.160.506
2bqvA1AProtease/0.506
3s85LK0Gag-Pol polyprotein/0.505
2wkz5AHGag-Pol polyprotein/0.503
4a6bQG8Gag-Pol polyprotein3.4.23.160.502
1ebyBEBGag-Pol polyprotein3.4.23.160.501
2qnnQN1Gag-Pol polyprotein3.4.23.160.500
2qhcAB1Protease/0.499
1c6yMK1Protease/0.497
3kddJZQGag-Pol polyprotein3.4.23.160.497
1hshMK1Gag-Pol polyprotein/0.495
2f8g017Gag-Pol polyprotein3.4.23.160.495
1sbgIM1Gag-Pol polyprotein/0.494
1t7i017Gag-Pol polyprotein3.4.23.160.494
1tcxIM1Gag-Pol polyprotein3.4.23.160.493
1b6kPI5Gag-Pol polyprotein3.4.23.160.492
4njvRITProtease/0.492
1w5xBE5Gag-Pol polyprotein3.4.23.160.491
1ebwBEIGag-Pol polyprotein3.4.23.160.490
1ebzBECGag-Pol polyprotein3.4.23.160.490
1muiAB1Protease/0.490
1xl5190Gag-Pol polyprotein3.4.23.160.490
1vikBAYGag-Pol polyprotein/0.489
1vijBAYGag-Pol polyprotein/0.488
3aidARQGag-Pol polyprotein3.4.23.160.488
1d4iBEGGag-Pol polyprotein3.4.23.160.487
2uy0HV1Gag-Pol polyprotein3.4.23.160.487
3cktYDPGag-Pol polyprotein3.4.23.160.487
1d4hBEHGag-Pol polyprotein3.4.23.160.486
1d4kPI8Gag-Pol polyprotein3.4.23.160.486
1d4jMSCGag-Pol polyprotein3.4.23.160.485
1ec3MS3Gag-Pol polyprotein3.4.23.160.485
3oxv478Gag-Pol polyprotein3.4.23.160.485
1ec0BEDGag-Pol polyprotein3.4.23.160.484
1sdvMK1Gag-Pol polyprotein3.4.23.160.484
1yt9OISGag-Pol polyprotein/0.484
3ggu017Gag-Pol polyprotein3.4.23.160.483
3kdcJZPGag-Pol polyprotein3.4.23.160.482
4njsG08Protease/0.482
2f80017Gag-Pol polyprotein3.4.23.160.481
3d1z017Gag-Pol polyprotein3.4.23.160.481
3jvwDMPGag-Pol polyprotein3.4.23.160.480
1bdrIM1Gag-Pol polyprotein3.4.23.160.479
1ivp1ZKGag-Pol polyprotein/0.479
3djkG55Gag-Pol polyprotein3.4.23.160.479
1ec2BEJGag-Pol polyprotein3.4.23.160.478
1w5vBE3Gag-Pol polyprotein3.4.23.160.478
2a4fAAUV-1 protease/0.478
3ggxGGXGag-Pol polyprotein/0.478
3vfb031Gag-Pol polyprotein3.4.23.160.478
2q5kAB1Protease/0.477
3zptM8YGag-Pol polyprotein3.4.23.160.476
4a6cQG9Gag-Pol polyprotein3.4.23.160.476
2bpv1INGag-Pol polyprotein3.4.23.160.475
2qi3MZ5Gag-Pol polyprotein/0.475
3vf5031Gag-Pol polyprotein3.4.23.160.475
2bb9AKCGag-Pol polyprotein3.4.23.160.474
2qd8065Gag-Pol polyprotein3.4.23.160.474
2r5q1UNGag-Pol polyprotein/0.474
1odw0E8Gag-Pol polyprotein3.4.23.160.473
1t7j478Gag-Pol polyprotein3.4.23.160.473
3a2oKNJGag-Pol polyprotein3.4.23.160.473
3kf03TLGag-Pol polyprotein/0.473
3kfn3TLGag-Pol polyprotein/0.473
3liqE14Protease/0.473
1qbsDMPGag-Pol polyprotein3.4.23.160.472
2aquDR7Gag-Pol polyprotein3.4.23.160.472
2cen4AHProtease/0.472
1hvrXK2Gag-Pol polyprotein/0.471
2rkfAB1Pol protein/0.471
3nls016Gag-Pol polyprotein3.4.23.160.471
3s54017Protease/0.471
3sa5A69Protease/0.471
2bpy3INGag-Pol polyprotein3.4.23.160.470
3qrmNK7Gag-Pol polyprotein3.4.23.160.470
1izhQ50Protease/0.469
1wbmBLLPol protein/0.469
1z1hHBBGag-Pol polyprotein3.4.23.160.469
2r5pMK1Gag-Pol polyprotein/0.469
3oxxDR7Gag-Pol polyprotein3.4.23.160.469
3zpsEQMGag-Pol polyprotein3.4.23.160.469
1bai0Q4Gag-Pro polyprotein/0.468
1mtrPI6Gag-Pol polyprotein3.4.23.160.468
1zsf0ZSGag-Pol polyprotein3.4.23.160.468
2b60RITPol polyprotein/0.468
2b7zMK1Gag-Pol polyprotein/0.468
2pqzG0GGag-Pol polyprotein3.4.23.160.468
1c6zROCProtease/0.467
1npvL27Gag-Pol polyprotein3.4.23.160.467
3dk1G05Gag-Pol polyprotein3.4.23.160.467
3el51UNGag-Pol polyprotein/0.467
3lixE17Protease/0.467
3mws017Pol protein/0.467
3qp0NI8Gag-Pol polyprotein3.4.23.160.467
1bdqIM1Gag-Pol polyprotein3.4.23.160.466
3livE16Protease/0.466
3nu9478Gag-Pol polyprotein3.4.23.160.466
3qrsNK8Gag-Pol polyprotein3.4.23.160.466
1c70L75Protease/0.465
1hpv478Gag-Pol polyprotein/0.465
2bpw1INGag-Pol polyprotein3.4.23.160.465
2hb3GRLProtease/0.465
2qd7065Gag-Pol polyprotein3.4.23.160.465
2r3tG4GGag-Pol polyprotein3.4.23.160.465
3ggaGGWGag-Pol polyprotein/0.465
3ndxRITGag-Pol polyprotein3.4.23.160.465
4a4qUX9Pol protein/0.465
4djoMK5Pol polyprotein/0.465
4ye3G04Gag-Pol polyprotein3.4.23.160.465
1a9mU0EGag-Pol polyprotein/0.464
1mesDMPGag-Pol polyprotein3.4.23.160.464
2fxdDR7Pol polyprotein/0.464
2xyfG40Gag-Pol polyprotein/0.464
3i6oGR6Gag-Pol polyprotein3.4.23.160.464
3linE13Protease/0.464
3nwq2NCGag-Pol polyprotein3.4.23.160.464
3slz3TLPutative gag-pro-pol polyprotein/0.464
2hc0AB2Protease/0.463
2qd6065Gag-Pol polyprotein3.4.23.160.463
3kfs3TLGag-Pol polyprotein/0.463
3zpuM8BGag-Pol polyprotein3.4.23.160.463
1k1u0Q4Gag-Pol polyprotein3.4.23.160.462
1k6tXN1Gag-Pol polyprotein3.4.23.160.462
1npa3NHGag-Pol polyprotein3.4.23.160.462
1npwLGZGag-Pol polyprotein3.4.23.160.462
1t7kBH0Gag-Pol polyprotein3.4.23.160.462
2f3kRO1Protease/0.462
3ekv478Gag-Pol polyprotein3.4.23.160.462
3nu5478Gag-Pol polyprotein3.4.23.160.462
3sa6F71Protease/0.462
4hla017Gag-Pol polyprotein3.4.23.160.462
1d4lPI9Gag-Pol polyprotein3.4.23.160.461
1hihC20Gag-Pol polyprotein/0.461
1sdtMK1Gag-Pol polyprotein3.4.23.160.461
2aidTHKGag-Pol polyprotein3.4.23.160.461
2q641UNGag-Pol polyprotein3.4.23.160.461
3bvb017Gag-Pol polyprotein3.4.23.160.461
3nwxKVSGag-Pol polyprotein3.4.23.160.461
3qn8NI7Gag-Pol polyprotein3.4.23.160.461
3sa755AProtease/0.461
3st5G89Gag-Pol polyprotein3.4.23.160.461
4kb9G79Protease/0.461
1a8g2Z4Gag-Pol polyprotein3.4.23.160.460
2avsMK1Gag-Pol polyprotein3.4.23.160.460
2bpz3INGag-Pol polyprotein3.4.23.160.460
2i4xKGQProtease/0.460
2z54AB1Gag-Pol polyprotein3.4.23.160.460
3oxw017Gag-Pol polyprotein3.4.23.160.460
1g2kNM1Gag-Pol polyprotein3.4.23.160.459
1jld0PPGag-Pol polyprotein/0.459
1meuDMPGag-Pol polyprotein3.4.23.160.459
2fdd385Pol protein/0.459
2hs2017Protease/0.459
2pk5075Protease/0.459
2pk6O33V-1 protease/0.459
3bgbLJGGag-Pol polyprotein3.4.23.160.459
3ekwDR7Gag-Pol polyprotein3.4.23.160.459
3ttp017Gag-Pol polyprotein3.4.23.160.459
4djqM86Pol polyprotein/0.459
4njt017Protease/0.459
1g35AHFGag-Pol polyprotein3.4.23.160.458
1hvjA78Gag-Pol polyprotein/0.458
2i4wKGQProtease/0.458
2ieo017Protease/0.458
2q54MU1Protease/0.458
1b6pPI7Gag-Pol polyprotein3.4.23.160.457
1hviA77Protease/0.457
1kzkJE2Gag-Pol polyprotein3.4.23.160.457
2p3d3TLProtease/0.457
2pwcG3GGag-Pol polyprotein3.4.23.160.457
3cyxROCGag-Pol polyprotein3.4.23.160.457
3em6017Gag-Pol polyprotein3.4.23.160.457
3i2l2NCProtease/0.457
3tl9ROCGag-Pol polyprotein3.4.23.160.457
4djpM73Pol polyprotein/0.457
1hsgMK1Gag-Pol polyprotein/0.456
1ohr1UNV-1 PROTEASE protein/0.456
2avvMK1Gag-Pol polyprotein3.4.23.160.456
2cej1AHPol protein/0.456
2q55MU0Protease/0.456
3qaaG04Gag-Pol polyprotein3.4.23.160.456
3qbfJHGGag-Pol polyprotein3.4.23.160.456
3uhl2NCGag-Pol polyprotein3.4.23.160.456
4k4p3TLGag-Pol polyprotein/0.456
1hosPHPGag-Pol polyprotein/0.455
2nmyROCProtease/0.455
2qnpQN2Gag-Pol polyprotein3.4.23.160.455
2xyeCXGGag-Pol polyprotein/0.455
3nu3478Gag-Pol polyprotein3.4.23.160.455
3nu4478Gag-Pol polyprotein3.4.23.160.455
3sa323XProtease/0.455
3vfa031Gag-Pol polyprotein3.4.23.160.455
1b6mPI6Gag-Pol polyprotein3.4.23.160.454
1hiiC20Gag-Pol polyprotein/0.454
2p3b3TLV-1 PROTEASE protein/0.454
2p3b3TLV-1 protease/0.454
2pym1UNGag-Pol polyprotein3.4.23.160.454
4hdfG52Gag-Pol polyprotein3.4.23.160.454
1fg80Q4Gag-Pol polyprotein3.4.23.160.453
2cem2AHPol protein/0.453
2fde385Gag-Pol polyprotein3.4.23.160.453
2z4o065Gag-Pol polyprotein3.4.23.160.453
3nuo478Gag-Pol polyprotein3.4.23.160.453
3s43478Protease/0.453
1fg62NCGag-Pol polyprotein3.4.23.160.452
1hxwRITGag-Pol polyprotein/0.452
1k2b0Q4Gag-Pol polyprotein3.4.23.160.452
1difA85Gag-Pol polyprotein/0.451
1k6pXN3Gag-Pol polyprotein3.4.23.160.451
1msmJE2Gag-Pol polyprotein3.4.23.160.451
2wl05AHGag-Pol polyprotein/0.451
3d1xROCGag-Pol polyprotein3.4.23.160.451
3ndtROCGag-Pol polyprotein3.4.23.160.451
1a940Q4Gag-Pol polyprotein3.4.23.160.450
1hvlA76Gag-Pol polyprotein/0.450
1qbu846Gag-Pol polyprotein3.4.23.160.450
2bpxMK1Gag-Pol polyprotein3.4.23.160.450
2fxeDR7Gag-Pol polyprotein3.4.23.160.450
2r38G4GGag-Pol polyprotein3.4.23.160.450
3ekqROCGag-Pol polyprotein3.4.23.160.450
3nduROCGag-Pol polyprotein3.4.23.160.450
3sa9A68Protease/0.450
4hdpG52Gag-Pol polyprotein3.4.23.160.450
4j55031Gag-Pol polyprotein3.4.23.160.450
1ajvNMBGag-Pol polyprotein3.4.23.160.449
1bv7XV6Gag-Pol polyprotein3.4.23.160.449
1sduMK1Gag-Pol polyprotein3.4.23.160.449
2bbbHH1Gag-Pol polyprotein3.4.23.160.449
2qi5MZ7Gag-Pol polyprotein/0.449
3nxe2NCProtease/0.449
3oxcROCProtease/0.449
3saa77FProtease/0.449
1k6cMK1Gag-Pol polyprotein3.4.23.160.448
1mrwK57Gag-Pol polyprotein3.4.23.160.448
2qak1UNGag-Pol polyprotein3.4.23.160.448
2uxzHI1Gag-Pol polyprotein3.4.23.160.448
3ekp478Gag-Pol polyprotein3.4.23.160.448
3nu6478Gag-Pol polyprotein3.4.23.160.448
4dqc017Gag-Pol polyprotein/0.448
1ajxAH1Gag-Pol polyprotein3.4.23.160.447
1metDMPGag-Pol polyprotein3.4.23.160.447
2qci065Gag-Pol polyprotein3.4.23.160.447
3mxeK54Gag-Pol polyprotein3.4.23.160.447
3o9cK20Pol polyprotein/0.447
4q1y017Gag-Pol polyprotein3.4.23.160.447
1hpxKNIGag-Pol polyprotein/0.446
1ivq0PXGag-Pol polyprotein/0.446
1proA88Gag-Pol polyprotein/0.446
2qhyMZ1Gag-Pol polyprotein/0.446
4dfg0JVGag-Pol polyprotein3.4.23.160.446
1bwaXV6Gag-Pol polyprotein3.4.23.160.445
2r43G3GGag-Pol polyprotein3.4.23.160.445
3em4DR7Gag-Pol polyprotein3.4.23.160.445
3lzv017Gag-Pol polyprotein3.4.23.160.445
4rvj478Protease/0.445
1hxbROCGag-Pol polyprotein3.4.23.160.444
1sguMK1Gag-Pol polyprotein3.4.23.160.444
2avm2NCGag-Pol polyprotein3.4.23.160.444
2qnqQN3Gag-Pol polyprotein3.4.23.160.444
3bva2NCGag-Pol polyprotein3.4.23.160.444
3i7eDJRGag-Pol polyprotein/0.444
3t3c017Gag-Pol polyprotein3.4.23.160.444
3upjU03Gag-Pol polyprotein/0.444
3wsjMK1Protease/0.444
4njuTPVProtease/0.444
1qbrXV6Gag-Pol polyprotein3.4.23.160.443
1t3r017Gag-Pol polyprotein3.4.23.160.443
1zsr0ZTGag-Pol polyprotein3.4.23.160.443
2pyn1UNGag-Pol polyprotein3.4.23.160.443
3el4ROCGag-Pol polyprotein3.4.23.160.443
4i8zG08Gag-Pol polyprotein3.4.23.160.443
2qhzMZ2Gag-Pol polyprotein/0.442
3d1yROCGag-Pol polyprotein3.4.23.160.442
3kfr3TLGag-Pol polyprotein/0.442
3nyg2NCGag-Pol polyprotein3.4.23.160.442
3pwrROCGag-Pol polyprotein3.4.23.160.442
3qroNK9Gag-Pol polyprotein3.4.23.160.442
3vf7031Gag-Pol polyprotein3.4.23.160.442
1bveDMPGag-Pol polyprotein3.4.23.160.441
1fej2NCGag-Pol polyprotein3.4.23.160.441
1iziQ50Gag-Pol polyprotein3.4.23.160.441
2qi0MZ3Gag-Pol polyprotein/0.441
3dcrKVSProtease/0.441
3ec0GRLGag-Pol polyprotein3.4.23.470.441
3nuj478Gag-Pol polyprotein3.4.23.160.441
1bvgDMPGag-Pol polyprotein3.4.23.160.440
1d4yTPVGag-Pol polyprotein3.4.23.160.440
1sh9RITGag-Pol polyprotein3.4.23.160.440
2ien017Gag-Pol polyprotein3.4.23.160.440
3dckKVIProtease/0.440
3o9bK2APol polyprotein/0.440
9hvp0E9Gag-Pol polyprotein/0.440