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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3nnwEDDMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3nnwEDDMitogen-activated protein kinase 14/1.000
3nnuEDBMitogen-activated protein kinase 14/0.680
3nnxEDDMitogen-activated protein kinase 14/0.621
1w82L10Mitogen-activated protein kinase 14/0.575
3p7bP7BMitogen-activated protein kinase 14/0.567
2yisYISMitogen-activated protein kinase 14/0.545
3uvr06FMitogen-activated protein kinase 14/0.523
3p5kP5KMitogen-activated protein kinase 14/0.520
3d83GK6Mitogen-activated protein kinase 14/0.518
3e9319BMitogen-activated protein kinase 14/0.512
3gcuR48Mitogen-activated protein kinase 14/0.508
3p79P79Mitogen-activated protein kinase 14/0.502
3p7aP7AMitogen-activated protein kinase 14/0.495
1kv2B96Mitogen-activated protein kinase 14/0.494
3npcB96Mitogen-activated protein kinase 92.7.11.240.494
3kq7KQ7Mitogen-activated protein kinase 14/0.493
3lffZ83Mitogen-activated protein kinase 14/0.489
2puuG2GMitogen-activated protein kinase 14/0.487
3hv4L51Mitogen-activated protein kinase 14/0.486
2yiwYIWMitogen-activated protein kinase 14/0.482
3p7cP7CMitogen-activated protein kinase 14/0.481
3p78P78Mitogen-activated protein kinase 14/0.475
3k3jF4CMitogen-activated protein kinase 14/0.474
1kv1BMUMitogen-activated protein kinase 14/0.473
1wbtWBTMitogen-activated protein kinase 14/0.473
1wbsLI2Mitogen-activated protein kinase 14/0.464
3gcvSS6Mitogen-activated protein kinase 14/0.459
3gi3B10Mitogen-activated protein kinase 14/0.459
3ugc046Tyrosine-protein kinase JAK2/0.459
1wbvLI3Mitogen-activated protein kinase 14/0.453
3wzeBAXVascular endothelial growth factor receptor 22.7.10.10.452
1wbnL09Mitogen-activated protein kinase 14/0.450
4eh90OQMitogen-activated protein kinase 14/0.449
3o8uBMUMitogen-activated protein kinase 14/0.448
4ehv0SJMitogen-activated protein kinase 14/0.445
2rc3NADCBS domain/0.442
4bbe3O4Tyrosine-protein kinase JAK2/0.441
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1n07FMNRiboflavin kinase2.7.1.260.440
4axfANPInositol-pentakisphosphate 2-kinase2.7.1.1580.440