sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 1.000 | |
| 3jvh | HHV | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.656 | |
| 3ke1 | 829 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.526 | |
| 1h48 | CDI | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.487 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1p7c | T5A | Thymidine kinase | / | 0.468 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.457 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.456 | |
| 4die | C5P | Cytidylate kinase | / | 0.456 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 2amt | 1AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.450 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.448 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.447 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.447 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.446 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.445 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.443 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.443 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 4ysw | NAI | Xanthine dehydrogenase/oxidase | / | 0.441 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.440 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.440 |