sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 1.000 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.559 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.532 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.465 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.464 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.452 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.451 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 1r2j | FAD | FkbI | / | 0.448 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.446 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.445 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 3arv | SAU | Chitinase A | / | 0.444 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.442 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.442 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.440 |