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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3g1mRF3HTH-type transcriptional regulator EthR

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3g1mRF3HTH-type transcriptional regulator EthR/1.000
3q0uLL3HTH-type transcriptional regulator EthR/0.707
3o8hO8HHTH-type transcriptional regulator EthR/0.649
3q0vLL4HTH-type transcriptional regulator EthR/0.643
3sfi3SFHTH-type transcriptional regulator EthR/0.635
3o8gO8GHTH-type transcriptional regulator EthR/0.629
3tp0FO5HTH-type transcriptional regulator EthR/0.590
3a1l2CCCytochrome P450/0.494
3ol5SAWCamphor 5-monooxygenase1.14.15.10.472
4dw60MNHTH-type transcriptional regulator EthR/0.472
3p6oETGCamphor 5-monooxygenase1.14.15.10.464
2z3uCRRCytochrome P450/0.463
3p6nDSOCamphor 5-monooxygenase1.14.15.10.463
3g1lRF2HTH-type transcriptional regulator EthR/0.459
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.459
3p6mDSOCamphor 5-monooxygenase1.14.15.10.456
1re9DSOCamphor 5-monooxygenase1.14.15.10.455
3g1oRF1HTH-type transcriptional regulator EthR/0.454
3tdaPN0Cytochrome P450 2D6/0.448
1o6qR17Squalene--hopene cyclase4.2.1.1290.445
3qm4PN0Cytochrome P450 2D6/0.445
4iaq2GM5-hydroxytryptamine receptor 1B/0.445
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
3iupNDPPossible NADH oxidoreductase/0.444
3p6pA6BCamphor 5-monooxygenase1.14.15.10.444
1n83CLRNuclear receptor ROR-alpha/0.441
2d1sSLULuciferin 4-monooxygenase1.13.12.70.441
4j6cSTRCytochrome P450 monooxygenase/0.441
2w4qCBWProstaglandin reductase 21.3.1.480.440
5ag6MYAGlycylpeptide N-tetradecanoyltransferase/0.440