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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3f1kNAPUncharacterized oxidoreductase YciK1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3f1kNAPUncharacterized oxidoreductase YciK11.000
3gy0NAPNAD(P)-dependent oxidoreductase/0.546
4hwkNAPSepiapterin reductase1.1.1.1530.506
1w4zNAPPutative ketoacyl reductase1.3.10.504
4j7xNAPSepiapterin reductase1.1.1.1530.501
4j7uNAPSepiapterin reductase1.1.1.1530.494
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.488
1x7hNDPPutative ketoacyl reductase1.3.10.484
3qrwNDPPutative ketoacyl reductase1.3.10.478
1ae1NAPTropinone reductase 1/0.473
2bd0NAPSepiapterin reductase/0.471
1n5dNDPCarbonyl reductase [NADPH] 1/0.469
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.469
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.468
1x7gNAPPutative ketoacyl reductase1.3.10.467
3lqfNADGalactitol dehydrogenase/0.466
4dc1NDPPutative ketoacyl reductase1.3.10.466
1g6kNADGlucose 1-dehydrogenase1.1.1.470.462
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.461
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.458
4qecNAPElxO/0.456
1oaaNAPSepiapterin reductase1.1.1.1530.455
3toxNAPPutative oxidoreductase/0.455
5idwNAPShort-chain dehydrogenase/reductase SDR/0.455
1wntNAPL-xylulose reductase1.1.1.100.452
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.451
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.450
1ipeNDPTropinone reductase 21.1.1.2360.449
3p19NDPPutative blue fluorescent protein/0.449
3sjuNDPKeto reductase/0.449
4o0lNDPNADPH-dependent 3-quinuclidinone reductase/0.447
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.446
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.445
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.445
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441