sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ez2 | ADP | Plasmid partition protein A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ez2 | ADP | Plasmid partition protein A | / | 1.000 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.465 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.448 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.444 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.443 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.440 |