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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3cjtSAHRibosomal protein L11 methyltransferase2.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3cjtSAHRibosomal protein L11 methyltransferase2.1.11.000
3egvSAHRibosomal protein L11 methyltransferase2.1.10.640
2nxeSAMRibosomal protein L11 methyltransferase2.1.10.524
3cjqSAHRibosomal protein L11 methyltransferase2.1.10.509
5bp9SAHPutative methyltransferase protein/0.482
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.455
3sxjSAMPutative methyltransferase/0.450
4h0nSAHDnmt2/0.449
5je3SAHMethyl transferase/0.444
4u7tSAHDNA (cytosine-5)-methyltransferase 3A2.1.1.370.441
3jv7NADSecondary alcohol dehydrogenase/0.440