Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3cbpSFGHistone-lysine N-methyltransferase SETD72.1.1.43

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3cbpSFGHistone-lysine N-methyltransferase SETD72.1.1.431.000
4j83SAMHistone-lysine N-methyltransferase SETD72.1.1.430.588
3m53SAHHistone-lysine N-methyltransferase SETD72.1.1.430.557
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.527
5jj0SAMHistone-lysine N-methyltransferase EHMT2/0.519
3ru0SFGHistone-lysine N-methyltransferase SMYD32.1.1.430.507
5jhnSAMHistone-lysine N-methyltransferase EHMT2/0.506
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.503
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.501
5jinSAMHistone-lysine N-methyltransferase EHMT2/0.492
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.490
3ribSAHN-lysine methyltransferase SMYD2/0.489
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.485
3hnaSAHHistone-lysine N-methyltransferase EHMT1/0.483
1mlvSAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.481
2igqSAHHistone-lysine N-methyltransferase EHMT1/0.481
3tg4SAMN-lysine methyltransferase SMYD2/0.475
2r3aSAMHistone-lysine N-methyltransferase SUV39H22.1.1.430.473
3fpdSAHHistone-lysine N-methyltransferase EHMT1/0.465
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.465
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.464
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.463
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.457
3kmtSAHHistone H3K27 methylase/0.455
4o30SAHProbable Histone-lysine N-methyltransferase ATXR52.1.1.430.455
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.450
4nv14TGFormyl transferase/0.450
5czySAMEukaryotic huntingtin interacting protein B/0.450
2h2jSFGRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.449
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.447
1ozvSAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.446
2fs4PZ1Renin3.4.23.150.445
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.443
4qenSAHHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH42.1.1.430.443
2h2eSA8Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.442
3ensENSCoagulation factor X3.4.21.60.442
3hl0NADMaleylacetate reductase/0.442
3s5wFADL-ornithine N(5)-monooxygenase/0.442
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.442
2bqzSAHN-lysine methyltransferase KMT5A/0.441
4ypeSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.440