sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 1.000 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.754 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.706 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.702 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.700 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.595 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.542 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.522 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.521 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.516 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.504 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.500 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.499 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.496 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.493 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.492 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.488 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.484 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.468 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.466 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.464 | |
| 3h7u | NAP | NADPH-dependent aldo-keto reductase, chloroplastic | / | 0.456 | |
| 5dp2 | NAP | CurF | / | 0.455 | |
| 2p5n | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 1ah4 | NAP | Aldose reductase | 1.1.1.21 | 0.452 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 4g5d | NDP | Prostaglandin F synthase | 1.1.1.188 | 0.445 | |
| 2clp | NDP | Aflatoxin B1 aldehyde reductase member 3 | / | 0.442 |