sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bj7 | COA | Diamine acetyltransferase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 1.000 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.638 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.615 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.599 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.498 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.495 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.492 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.485 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.472 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.468 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.467 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.463 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.463 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.462 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.459 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.459 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.457 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.457 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.453 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.452 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.450 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.447 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.447 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.447 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.446 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.446 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.442 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 |