sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ang | DCC | Transcriptional repressor, TetR family |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ang | DCC | Transcriptional repressor, TetR family | / | 1.000 | |
| 3anp | DCC | Transcriptional repressor, TetR family | / | 0.621 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.486 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.465 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.458 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.457 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.453 | |
| 4o7u | THF | Thymidylate synthase | / | 0.453 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.452 | |
| 4iah | 1DX | Alr2278 protein | / | 0.452 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.451 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.445 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.445 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.444 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.444 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.442 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.441 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.440 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.440 |