Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ai2NDPNADPH-sorbose reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ai2NDPNADPH-sorbose reductase/1.000
3ai3NDPNADPH-sorbose reductase/0.635
3toxNAPPutative oxidoreductase/0.500
3lqfNADGalactitol dehydrogenase/0.488
1w4zNAPPutative ketoacyl reductase1.3.10.483
1g6kNADGlucose 1-dehydrogenase1.1.1.470.478
3vdqNAD3-hydroxybutyrate dehydrogenase/0.478
1xkqNDPUncharacterized protein/0.476
3w8eNAD3-hydroxybutyrate dehydrogenase/0.474
4j7uNAPSepiapterin reductase1.1.1.1530.473
1xg5NAPDehydrogenase/reductase SDR family member 11/0.469
4b79NADProbable short-chain dehydrogenase/0.465
2yutNAPPutative short-chain oxidoreductase/0.464
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
4esoNAPPutative oxidoreductase/0.463
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.462
4j7xNAPSepiapterin reductase1.1.1.1530.462
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.457
1ipeNDPTropinone reductase 21.1.1.2360.455
1x7hNDPPutative ketoacyl reductase1.3.10.453
1geeNADGlucose 1-dehydrogenase1.1.1.470.451
1x7gNAPPutative ketoacyl reductase1.3.10.449
1gcoNADGlucose 1-dehydrogenase1.1.1.470.445
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.445
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
5idwNAPShort-chain dehydrogenase/reductase SDR/0.445
4bmvNAPShort-chain dehydrogenase/0.442
4qecNAPElxO/0.442
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.440