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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3a1nNADNDP-sugar epimerase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3a1nNADNDP-sugar epimerase/1.000
3a4vNADNDP-sugar epimerase/0.666
3a9wNADNDP-sugar epimerase/0.544
3ajrNADNDP-sugar epimerase/0.531
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.526
5lc1NADL-threonine 3-dehydrogenase/0.482
2yy7NADL-threonine dehydrogenase/0.476
1wntNAPL-xylulose reductase1.1.1.100.472
2wsbNADGalactitol dehydrogenase/0.471
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.470
2p5uNADUDP-glucose 4-epimerase/0.470
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.469
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.465
3wmxNADNAD dependent epimerase/dehydratase/0.459
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.457
5jlaNADPutative short-chain dehydrogenase/reductase/0.456
4gh5NADShort-chain dehydrogenase/reductase SDR/0.451
1e3wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.450
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.450
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.446
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.444