sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 1.000 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.679 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.643 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.639 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.632 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.625 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.606 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.593 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.563 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.479 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.463 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.458 | |
| 4j7h | TRH | PCZA361.3 | / | 0.453 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.453 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.451 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.451 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.450 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.450 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.440 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.440 |