sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 1.000 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.679 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.632 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.623 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.622 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.621 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.605 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.598 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.520 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.467 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.466 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.458 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.458 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.457 | |
| 1a2n | TET | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.453 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.449 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.448 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.447 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 1t57 | FMN | Conserved protein | / | 0.440 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 |