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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2zfaFMNLactate oxidase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2zfaFMNLactate oxidase/1.000
2nliFMNLactate oxidase/0.548
2j6xFMNLactate oxidase/0.538
4rjeFNRLactate oxidase/0.482
2e77FMNLactate oxidase/0.481
1goxFMNPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.477
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.476
1h50FMNPentaerythritol tetranitrate reductase/0.470
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.469
4yl2FMNLactate oxidase/0.466
1z48FMNNADPH dehydrogenase/0.457
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.452
2gjlFMNNitronate monooxygenase1.13.12.160.450
1szgFNSCytochrome b2, mitochondrial1.1.2.30.449
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.446
1vyrFMNPentaerythritol tetranitrate reductase/0.446
3p74FMNPentaerythritol tetranitrate reductase/0.444
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.443
3p8iFMNPentaerythritol tetranitrate reductase/0.442
1h63FMNPentaerythritol tetranitrate reductase/0.441
4jicFMNGTN Reductase/0.440