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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.37

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.371.000
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.584
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.577
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.569
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.559
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.555
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.549
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.537
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.531
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.509
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.494
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.489
2dvlFADAcyl-CoA dehydrogenase/0.478
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.452
1rfuADPPyridoxal kinase2.7.1.350.451
1cf3FADGlucose oxidase1.1.3.40.446
2d29FADAcyl-CoA dehydrogenase/0.446
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
2jb4A14Isopenicillin N synthase1.21.3.10.440