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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2y5kYCUFructose-1,6-bisphosphatase 13.1.3.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2y5kYCUFructose-1,6-bisphosphatase 13.1.3.111.000
2fhyA37Fructose-1,6-bisphosphatase 13.1.3.110.547
2wbbRO3Fructose-1,6-bisphosphatase 13.1.3.110.500
2wbdRO5Fructose-1,6-bisphosphatase 13.1.3.110.477
4g3jVNTLanosterol 14-alpha-demethylase/0.451
1xe55FEPlasmepsin-23.4.23.390.446
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.445
3gw9VNILanosterol 14-alpha-demethylase/0.444
4g7gVFVLanosterol 14-alpha-demethylase/0.441
3t2zFADSulfide-quinone reductase/0.440