Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2y1w | 849 | Histone-arginine methyltransferase CARM1 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 1.000 | |
2y1x | 845 | Histone-arginine methyltransferase CARM1 | / | 0.530 | |
4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.457 | |
4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.457 | |
3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.442 |