scPDB - Distribution of Binding site Similarity values of 2xui entry / Site 2

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2xui	TZ5	Acetylcholinesterase	3.1.1.7

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2xui	TZ5	Acetylcholinesterase	3.1.1.7	1.000
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.623
2xuk	TZ5	Acetylcholinesterase	3.1.1.7	0.612
2xuq	TZ4	Acetylcholinesterase	3.1.1.7	0.550
4arb	C57	Acetylcholinesterase	3.1.1.7	0.537
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.533
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.527
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.525
2ha6	SCK	Acetylcholinesterase	3.1.1.7	0.507
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.505
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.504
1eve	E20	Acetylcholinesterase	3.1.1.7	0.503
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.503
1q83	TZ5	Acetylcholinesterase	3.1.1.7	0.497
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.495
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.494
1w4l	GL8	Acetylcholinesterase	3.1.1.7	0.493
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.493
1h22	E10	Acetylcholinesterase	3.1.1.7	0.492
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.490
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.488
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.485
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.483
1ut6	A8N	Acetylcholinesterase	3.1.1.7	0.480
4ara	C56	Acetylcholinesterase	3.1.1.7	0.454
2ckm	AA7	Acetylcholinesterase	3.1.1.7	0.447
2xug	TZ4	Acetylcholinesterase	3.1.1.7	0.446
4b7z	Q4Q	Acetylcholinesterase	3.1.1.7	0.444