Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2w93TPPPyruvate decarboxylase isozyme 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2w93TPPPyruvate decarboxylase isozyme 1/1.000
2vk8TPPPyruvate decarboxylase isozyme 1/0.574
2vk4TPPPyruvate decarboxylase4.1.1.10.554
1pvdTPPPyruvate decarboxylase isozyme 1/0.553
1qpbTPPPyruvate decarboxylase isozyme 1/0.545
1ovmTPPIndole-3-pyruvate decarboxylase4.1.1.740.542
1pydTDPPyruvate decarboxylase isozyme 1/0.510
4zp1TPPPyruvate decarboxylase4.1.1.10.493
4cokTPPPyruvate decarboxylase/0.462
2q5qTPWIndole-3-pyruvate decarboxylase4.1.1.740.460
2ag0TPPBenzaldehyde lyase/0.458
3oe1TDLPyruvate decarboxylase4.1.1.10.453
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.451
2givACOHistone acetyltransferase KAT8/0.449
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.447
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.442