sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 1.000 | |
| 2qei | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.805 | |
| 2qju | DSM | Na(+):neurotransmitter symporter (Snf family) | / | 0.508 | |
| 2q72 | IXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.504 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.474 | |
| 4l9q | 9TP | Serum albumin | / | 0.466 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.450 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.449 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.449 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.447 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.446 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 1fr8 | GDU | Beta-1,4-galactosyltransferase 1 | / | 0.440 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.440 |