sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 1.000 | |
| 2olr | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.611 | |
| 1ayl | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.569 | |
| 2olq | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.553 | |
| 1aq2 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.541 | |
| 1ytm | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.541 | |
| 1os1 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.538 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.501 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.480 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.464 | |
| 4die | C5P | Cytidylate kinase | / | 0.464 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.463 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.462 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.460 | |
| 2bxo | OPB | Serum albumin | / | 0.459 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.459 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.455 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.454 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.454 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.454 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.453 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.450 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.450 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.449 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.448 | |
| 2j4d | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.448 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.447 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.447 | |
| 2rc3 | NAD | CBS domain | / | 0.447 | |
| 4ohv | ANP | Protein clpf-1 | / | 0.447 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2osb | AP5 | Adenylate kinase | / | 0.445 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.445 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.445 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.444 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4dwv | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 4jky | ADP | Adenylate kinase | / | 0.444 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.443 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.443 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.442 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.442 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4cta | ATP | CinA-like protein | / | 0.442 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4wxl | BB2 | Peptide deformylase | / | 0.441 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4ac0 | MIY | Tetracycline repressor protein class B from transposon Tn10 | / | 0.440 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.440 | |
| 4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
| 5cyo | GDP | Septin-9 | / | 0.440 |