sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.536 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.523 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.501 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.483 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.482 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.470 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.461 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.453 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.451 | |
| 3tgp | GNP | GTPase HRas | / | 0.450 | |
| 4xvq | GNP | GTPase HRas | / | 0.450 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.448 | |
| 4itr | GDP | Cell division control protein 42 homolog | / | 0.448 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.447 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.445 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.440 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.440 |