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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ovhAS0Progesterone receptor

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ovhAS0Progesterone receptor/1.000
2ovmAS0Progesterone receptor/0.658
1nhz486Glucocorticoid receptor/0.508
4a2jAS0Progesterone receptor/0.485
2w8y486Progesterone receptor/0.484
4ipw1G7Mycocyclosin synthase1.14.21.90.468
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.462
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1kkq471Peroxisome proliferator-activated receptor alpha/0.450
3vt8YI3Vitamin D3 receptor/0.449
2hw2RFPRifampin ADP-ribosyl transferase/0.448
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1psa0ZLPepsin A3.4.23.10.446
3bc3OPTCathepsin L13.4.22.150.446
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
4bfvZVVPantothenate kinase2.7.1.330.444
4iarERM5-hydroxytryptamine receptor 1B/0.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.443
4uymVOR14-alpha sterol demethylase Cyp51B/0.443
1qrpHH0Pepsin A-43.4.23.10.442
1xe65FPPlasmepsin-23.4.23.390.442
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4a8v2ANMajor pollen allergen Bet v 1-J/0.440
4ia7BIVVitamin D3 receptor A/0.440