Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2osbAP5Adenylate kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2osbAP5Adenylate kinase/1.000
2qajAP5Adenylate kinase/0.669
2eu8AP5Adenylate kinase/0.597
2oo7AP5Adenylate kinase/0.571
4mkgAP5Adenylate kinase/0.563
4qbiAP5Adenylate kinase/0.563
3dkvAP5Adenylate kinase/0.556
3dl0AP5Adenylate kinase/0.553
3hpqAP5Adenylate kinase/0.544
4mkfAP5Adenylate kinase/0.540
1akeAP5Adenylate kinase/0.539
4x8oAP5Adenylate kinase/0.537
4ikeADPAdenylate kinase/0.533
4w5jAP5Adenylate kinase/0.532
4qbhAP5Adenylate kinase/0.529
4nu0AP5Adenylate kinase/0.524
1p3jAP5Adenylate kinase/0.521
1e4yAP5Adenylate kinase/0.520
1dvrATFAdenylate kinase/0.511
4jl6ADPAdenylate kinase/0.510
1ankANPAdenylate kinase/0.509
4jl5ADPAdenylate kinase/0.508
4jkyADPAdenylate kinase/0.507
4cf7ADPAdenylate kinase/0.502
4jldADPAdenylate kinase/0.494
3tlxADPAdenylate kinase 2/0.492
2eckADPAdenylate kinase/0.491
1zioAP5Adenylate kinase/0.488
2akyAP5Adenylate kinase/0.458
4loh1SYStimulator of interferon genes protein/0.449
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
2rgxAP5Adenylate kinase/0.440
4x8lAP5Adenylate kinase/0.440