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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2j7pGNPSignal recognition particle protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2j7pGNPSignal recognition particle protein/1.000
2j7pGNPSignal recognition particle receptor FtsY/1.000
1okkGCPSignal recognition particle protein/0.534
1okkGCPSignal recognition particle receptor FtsY/0.534
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.471
5l3sGNPSignal recognition particle receptor FtsY/0.463
1rj9GCPSignal recognition particle receptor FtsY/0.451
1fy7COAHistone acetyltransferase ESA1/0.446
4uyf73BBromodomain-containing protein 2/0.445
5k5zANPUncharacterized protein/0.442
1zioAP5Adenylate kinase/0.441
2w06FRVCyclin-dependent kinase 22.7.11.220.440
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440