sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2icy | UPG | UTP--glucose-1-phosphate uridylyltransferase 2 | 2.7.7.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2icy | UPG | UTP--glucose-1-phosphate uridylyltransferase 2 | 2.7.7.9 | 1.000 | |
| 2icx | UTP | UTP--glucose-1-phosphate uridylyltransferase 2 | 2.7.7.9 | 0.602 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.470 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.448 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.443 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2xvv | 9DN | Serum albumin | / | 0.440 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.440 |