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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2i0zFADNAD(FAD)-utilizing dehydrogenases

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2i0zFADNAD(FAD)-utilizing dehydrogenases/1.000
4cnjFADL-amino acid oxidase/0.493
1d4cFADFumarate reductase flavoprotein subunit1.3.5.40.471
4cnkFADL-amino acid oxidase/0.465
3lb8FADPutidaredoxin reductase1.18.1.50.463
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.452
1cc2FADCholesterol oxidase1.1.3.60.449
2bacFADPutative aminooxidase/0.449
1e1lFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
5j60FADThioredoxin reductase/0.445
1f3pFADFerredoxin reductase/0.444
1qo8FADFumarate reductase flavoprotein subunit/0.443
4u2sFDACholesterol oxidase1.1.3.60.443
2babFADPutative aminooxidase/0.442
2wesFADTryptophan 5-halogenase/0.441
1yqzFADCoenzyme A disulfide reductase/0.440